PIFELTRO is a once daily pill. You and your doctor can decide if PIFELTRO could be right for you.
Your health and HIV-1
Whether you take over-the-counter or doctor-prescribed medicines for other conditions, it is important that you talk to your doctor about all of your medicines.
PIFELTRO can be taken with a wide range of common, non-HIV-1 medicines, such as:
- Proton pump inhibitors for heartburn (pantoprazole)
- Oral contraceptives for birth control (ethinyl estradiol and levonorgestrel)
- Methadone for pain management
- Statins for high cholesterol (atorvastatin)
- Metformin for diabetes (metformin hydrochloride)
Do not take PIFELTRO if you are taking one of the following medicines: carbamazepine, oxcarbazepine, phenobarbital, phenytoin, enzalutamide, rifampin, rifapentine, mitotane, St. John’s wort. Ask your doctor or pharmacist if you are not sure if your medicine is one that is listed above. If you have taken any of the medicines in the past 4 weeks, talk to your doctor or pharmacist before starting PIFELTRO.
How to take PIFELTRO
- Take PIFELTRO every day exactly as your doctor tells you to take it. Take PIFELTRO 1 time each day, at about the same time every day.
- Tell your doctor if you have taken rifabutin in the past 4 weeks.
- If you take the medicine rifabutin during treatment with PIFELTRO, take PIFELTRO 2 times each day, about 12 hours apart, as prescribed by your doctor. You may not have enough doravirine in your blood if you take rifabutin during treatment with PIFELTRO.
- Do not change your dose or stop taking PIFELTRO without talking to your doctor. Stay under a healthcare provider’s care when taking PIFELTRO.
- Take PIFELTRO on a regular dosing schedule as instructed by your doctor. Do not miss doses.
- If you miss a dose of PIFELTRO, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose at your regular time.
- Get your PIFELTRO refilled from your doctor or pharmacy before you run out.
- This is very important because the amount of virus in your blood may increase if the medicine is stopped for even a short time. The virus may develop resistance to PIFELTRO and become harder to treat.